BCI-based neurofeedback (NFB) is a promising tool for counteracting neurological symptoms and informing neurorehabilitation strategies. Efforts have been made to improve BCI usability, by providing guidelines and predictors of performance. Yet, neurofeedback remains barely used in clinical settings and by patients in their daily life. In this workshop, we tackled the current challenges in clinical BCI research by identifying and discussing the key methodological and psychobiological aspects to foster its efficacy. We dealt with conceptual biases in clinical protocol designs. All the resources are available on [Github](https://github.com/mccorsi/BCI-2023-Clinical-BCI-workshop)!